Veteran buttoned-down LAPD detective Roger Murtaugh is partnered with unhinged cop Martin Riggs, who -- distraught after his wife's death -- has a death wish and takes unnecessary risks with criminals at every turn. The odd couple embark on their first homicide investigation as partners, involving a young woman known to Murtaugh with ties to a drug and prostitution ring.
Set in Kansas City in 1933, Eastwood plays a police lieutenant known simply by his last name, Speer. Reynolds plays a former cop turned private eye named Mike Murphy. Both Speer and Murphy served on the force together and were once good friends, but are now bitter enemies. When Murphy's partner is slain they team up again to fight the mob.
When a young rape victim takes justice into her own hands and becomes a serial killer, it's up to Dirty Harry Callahan, on suspension from the SFPD, to bring her to justice.